The Primary Healthcare (PHC) EML and STGs allow for the management of patients with relatively common conditions at primary level of care. They also guide referral of patients with more complex or uncommon conditions to facilities with the skills and resources to provide further investigation and management. As such, they serve as a progression to Adult and Paediatric hospital level EMLs and STGs. The PHC STGs and EML should be used by healthcare workers providing care at clinics, community health centres, and gateway clinics at hospitals. Pharmaceutical and Therapeutics Committees (PTCs) are responsible for ensuring the availability of medicines listed in the PHC EML at those facilities, as well as at higher levels of care.

*Note: The updated chapters contained in this folder supersedes those contained in the complete PDF.

Medicine Review and Costing Analyses
A Medicine Review is the process whereby relevant clinical evidence on a specific medicine is gathered and analysed, with the findings presented in a Medicine Review Technical Report that is presented to the NEMLC for appraisal. A Medicine Review is conducted to determine if a medicine should be added or deleted from the EML for a specific indication. 

Costing analyses compare the cost of two regiments or formulations. Aspects like costs of treatments and human resources are considered, and clearly state the assumptions made when conducting the analysis.

The National Drug Policy makes provision for an Essential Drugs Program (EDP), which is a key component in promoting rational medicines use. Each treatment guideline in the Paediatric Hospital Level Standard Treatment Guidelines (STGs) and Essential Medicines List (EML) has been designed as a progression in care from the current Primary Health Care (PHC) STGs and EML. In addition, where a referral is recommended, the relevant medicines have either been reviewed and included on the Tertiary level EML, or are in the process of being reviewed. The STGs serve as a standard for practice, but do not replace sound clinical judgment. It is important to remember that the recommended treatments provided in this book are guidelines only, and are based on the assumption that prescribers are competent to handle patients with the relevant conditions.

*Note: The updated chapters contained in this folder supersedes those contained in the complete PDF.

South Africa has committed to “achieve universal health coverage including financial risk protection, access to quality essential health-care services and access to safe, effective, quality and affordable essential medicines and vaccines for all“, one of the 17 Sustainable Development Goals set out by the United Nations. As such, it gives us great pleasure to present the Fifth Edition of the Adult Standard Treatment Guidelines and Essential Medicines List for Hospital Level care, which aims to enable equitable access to safe, effective, and affordable essential medicines at hospital level across South Africa. The Adult Standard Treatment Guidelines and Essential Medicines List for Hospital Level provide a platform for transparency to enable equitable access to safe, effective, and affordable treatment options at hospital level taking into consideration the changing clinical needs of our population and the pragmatic implications of the introducing a new health technology.

*Note: The updated chapters contained in this folder supersedes those contained in the complete PDF.

Medicine Review and Costing Analyses
A Medicine Review is the process whereby relevant clinical evidence on a specific medicine is gathered and analysed, with the findings presented in a Medicine Review Technical Report that is presented to the NEMLC for appraisal. A Medicine Review is conducted to determine if a medicine should be added or deleted from the EML for a specific indication. 

Costing analyses compare the cost of two regiments or formulations. Aspects like costs of treatments and human resources are considered, and clearly state the assumptions made when conducting the analysis.

The evidence-based medicine recommendations included in the Tertiary and Quaternary Essential Medicines List (EML) are reviewed through the transparent critical appraisal of global evidence, using a systematic evidence-to-decision framework. The Tertiary and Quaternary Hospital Level EML, which constitutes a list of essential medicines for approved indication, is ratified and distributed quarterly following NEMLC approval. It guides the selection, procurement and use of medicines at Tertiary and Quaternary level health establishments in the public sector in South Africa.

Medicine Review and Costing Analyses
A Medicine Review is the process whereby relevant clinical evidence on a specific medicine is gathered and analysed, with the findings presented in a Medicine Review Technical Report that is presented to the NEMLC for appraisal. A Medicine Review is conducted to determine if a medicine should be added or deleted from the EML for a specific indication.

Costing analyses compare the cost of two regiments or formulations. Aspects like costs of treatments and human resources are considered, and clearly state the assumptions made when conducting the analysis.

The National Essential Medicines List Committee (NEMLC) is a non-statutory, advisory committee appointed by the Minister of Health, responsible for the development and management of the national Standard Treatment Guidelines (STGs) and Essential Medicines List (EML), which guide clinical practice at all public sector health establishments and inform procurement of medicines in the public sector.

NHI – EDP – GovPol – NEMLC Policies

NHI – EDP – GovPol – HTA